When the liver is stung by dengue fever
Dengue fever is a prevalent arboviral illness that causes considerable morbidity in tropical areas. Dengue fever is spread through the bite of the common Aedes aegypti mosquito in tropical and subtropical settings. In September 2022, around 63,280 cases of dengue fever were reported in India.
Patients have gastrointestinal discomfort (18-63%), nausea/vomiting (49-58%), and appetite loss. Mild dengue had much more symptoms than severe dengue, including stomach discomfort and anorexia (an eating problem).
Clinical jaundice occurred in 1.7-17% of the groups, with increased bilirubin in 48%. 12.9% of patients had low protein or albumin levels. There was also a tendency toward greater blood clotting.
Men and women were equally affected by liver impairment.
Is it possible for dengue to induce liver disease? Dengue fever has caused life-threatening hemorrhage, low blood pressure, and organ failure in severe cases. It causes significant damage to several organ systems, particularly the liver, which can result in hepatic instability and abrupt liver failure.
Liver symptoms (fatty liver) are produced by the virus's immunologic damage or direct viral toxicity. The complete spectrum of dengue liver illness can vary from asymptomatic elevated liver transaminases to abrupt liver failure.
Liver enlargement is a clinical indication of liver failure that can occur in both moderate and severe illness, but is more prevalent in the former.
In 4-52% of adult dengue patients, the liver is enlarged. Elevated liver function test levels were the most prevalent abnormality. Elevated levels were discovered in 45-96% of all cases. They restored to normal values in the majority of instances within three weeks.
Patients with acute dengue fever liver illness should be hospitalized, treated extensively, and continually monitored for signs and symptoms of liver failure and consequences. Regular liver function tests are essential for monitoring the course of liver disease.
The condition is mostly treated with supportive care, and the outcome is typically favourable. Antiviral drugs may be provided to slow the course of the disease and decrease inflammation.
Drugs that aggravate liver disease should be diagnosed and used with caution. N-acetylcysteine is vital in therapy, most likely through numerous pathways. N-acetylcysteine improves liver damage in dengue hepatitis patients, although this benefit does not appear to affect disease progression.
Adequate diet is essential for liver support and recovery. If the liver is significantly damaged, blood transfusions to replenish lost blood or a liver transplant may be required in rare situations.
When the liver is stung by dengue fever
N-acetylcysteine has an essential role in the treatment of acute dengue fever liver damage, potentially by lowering oxidative stress, acting as a direct antiviral, and enhancing hepatic blood flow. It might be utilized to cure the liver failure caused by dengue fever for good.
Why is the liver so vulnerable in dengue fever?
Dengue fever liver damage mechanisms include direct viral or host immune response impacts on liver cells, reduced blood flow, hypoxia owing to metabolic acidosis and/or hypotension, or local vascular leakage in the liver [5, 7, 10, 14, 22].
Is it possible for dengue to induce liver failure?
Acute liver failure caused by dengue infection was more common in young adults (mean age 29 years). The average interval between the beginning of fever and the onset of acute liver failure was 7.5 days. Acute liver failure was more common in patients with severe dengue fever (P 0.001).
Is it possible for dengue fever to induce hepatitis?
Acute dengue virus infection frequently causes liver damage, which can result in deadly acute liver failure. A variety of causes are known to contribute to liver dysfunction, including hypoxia damage from decreasing blood flow, direct virus infection, and immune-mediated damage.
How long does the liver take to recover from dengue fever?
Elevated AST levels have been found in 63-97% of patients and 45-96% of patients, respectively. Most studies show that the rise in AST is higher than the increase in ALT and more prominent in the first week after infection, but recovers to normal levels within three weeks.
How can liver damage be repaired?
4 stages to liver repair
- Don't consume alcohol. The best thing you can do to protect your liver from potential harm is to avoid drinking alcohol.
- Avoid other potentially dangerous chemicals.
- Maintain a nutritious diet.
- Exercising in moderation is advised.
Which organ is the most vulnerable to dengue?
In deadly dengue, immunological processes attack the liver. The liver is one of the primary targets of DENV infection and the organ most commonly damaged by the illness.
What is the most effective technique to recover from dengue fever?
Make sure you're getting enough fluids. To maintain fluid balance, consume lots of fluids (water, isotonic drinks, juices, and soups). Avoid dehydrating beverages such as tea, coffee, alcohol, and sugary drinks. If nausea or vomiting stops you from drinking, intravenous fluids can be administered.
What is the duration of dengue fever?
Dengue fever symptoms begin four to ten days after a mosquito bite and might persist three to seven days.
What is the most effective technique to recover from dengue fever?
Make sure you're getting enough fluids. To maintain fluid balance, consume lots of fluids (water, isotonic drinks, juices, and soups). Avoid dehydrating beverages such as tea, coffee, alcohol, and sugary drinks. If nausea or vomiting stops you from drinking, intravenous fluids can be administered.
What is the duration of dengue fever?
Dengue fever symptoms begin four to ten days after a mosquito bite and might persist three to seven days.
Is banana permitted in dengue?
According to a research titled "Prevention and Control of Dengue via Nutritional Therapy," fruits including apple, banana, orange, pomegranate, papaya, and kiwi, as well as their juices, can help heal dengue.
What is the best dengue drink?
Coconut water is the most effective therapy for restoring the body's water balance. Patients suffering from dengue should consume extra coconut water in addition to other rehydration liquids to recover rapidly.
Is egg beneficial to dengue patients?
Dengue patients can eat eggs on a regular basis, but they should avoid the yolk.
Is hot water beneficial in the treatment of dengue? Increase your fluid intake and replace plain water with hot water. But be cautious. Dengue fever can swiftly worsen when the initial symptoms arise. As a result, it's critical to contact a doctor as soon as symptoms emerge.
If I have dengue fever, how should I sleep?
While a fever is present, let the ill kid or adult to relax and sleep behind a net or apply insect repellent. Remove any mosquitoes from the home and empty patio water containers. Install screens on windows and doors to keep mosquitos out.
What soup is effective against dengue?
Nandu collu soup is prepared with chopped horse grass and crab meat, as well as broth. The finest traditional dengue treatment is crab meat in papaya soup.
Can garlic be used to treat dengue fever?
Garlic was originally thought to be a therapy for dengue virus infections because garlic meals can inhibit nitric oxide synthesis, lowering the expression of inducible nitric oxide synthase (iNOS).